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Florida Geriatrics Society 

Advancing Geriatric Care in Florida Since 1989 

Recipient of the 2024 American Geriatrics Society State Affiliate Achievement Award 

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Florida Geriatrics Society Healthcare Professionals Forum  -

This Forum is a benefit to our FGS members and those who focus on the health and well-being of older adults in Florida. 

Osteoporosis Tx

  • 05/13/2025 11:45 PM
    Quote
    Reply # 13498865 on 13475477
    NS

    My understanding:  5 years for oral bisphosphonate therapy and 3 years for IV bisphosphonate therapy prior to considering a drug holiday. 

    Please share a recent reference, if you have one. This is a common clinical scenario but not sure there is consensus about duration of treatment. 

    Duration of Bisphosphonate Drug Holidays in Osteoporosis Patients: A Narrative Review of the Evidence and Considerations for Decision-Making JCM 2021

    https://pmc.ncbi.nlm.nih.gov/articles/PMC7963175/

    How Long Should Bisphosphonate Treatment be Continued For? NHS Trust 

    https://www.nbt.nhs.uk/clinicians/services-referral/osteoporosis-clinicians/how-long-should-bisphosphonate-treatment-be

    This is an old reference. Duration of Bisphosphonate Therapy. AFP 2018.

    https://www.aafp.org/pubs/afp/issues/2018/0401/od1.html 
  • 03/17/2025 4:39 AM
    Quote
    Message # 13475477
    Jonathan Seth Appelbaum, MD

    Let's try a clinical topic:

    In your practice, how long do you keep your patients with osteoporosis on bisphosphonate treatment?

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